In the pharmaceutical industry, the USP <643> total organic carbon test enables manufacturers to measure the total organic carbon content present in their water.
Pharmaceutical companies use USP <643> testing as an indirect way to measure the level of organic content in the water they plan to use. It is a simple and efficient way to monitor water for organic contamination. Organizations must remain vigilant, always contending with organic material that comes directly from the water source, or contamination entering through their distribution and purification systems, as well as potential biofilm buildup.
There are one primary method to measure total organic carbon:
- Subtract the amount of inorganic carbon from the total carbon measured (which includes inorganic and organic carbon).